Science
Forest therapy began as shinrin-yoku—forest bathing—in the 1980s in Japan. It was developed to combat the effects of overwork on physical and mental health. Immunologist Qing Li, M.D., Ph.D., with Nippon Medical School in Tokyo, is widely considered the leading expert on the science of forest therapy. He and other scientists have been studying how nature and forests can improve human health for more than 20 years.
Forest therapy: A mindful practice backed by research
Forest therapy—also known as shinrin-yoku or forest bathing—is a guided, mindful practice that invites people to slow down and engage their senses in natural environments. Over the past several decades, researchers across Japan, Europe, and North America have studied how time spent in forests and green spaces affects human physiology and psychology.
A growing body of peer-reviewed research suggests that intentional time in nature may support overall health and well-being by helping regulate stress, support immune function, improve mood, and enhance cognitive and emotional resilience. The findings below summarize areas where benefits have been most consistently observed.
Stress regulation and nervous system balance
One of the most well-documented effects of forest therapy is its ability to support stress reduction and nervous system regulation.
Research suggests forest therapy may help:
• Lower blood pressure and heart rate
• Reduce cortisol, a key stress hormone
• Shift the nervous system away from “fight or flight” and toward a calmer, restorative state
• Decrease activity in the amygdala, the part of the brain involved in fear and threat detection
• Increase feelings of relaxation, safety, and emotional balance
Multiple field studies and meta-analyses indicate that even short, slow walks in forested environments can produce measurable physiological changes associated with reduced stress and improved emotional regulation.
Immune system support
Research has also shown that time spent in forest environments may positively influence immune function. Observed effects include:
• Increased activity of natural killer (NK) cells, which play a role in immune defense
• Enhanced expression of proteins associated with antiviral and anticancer activity
• Effects that may persist for days or weeks following forest exposure
These immune-related findings are thought to be influenced by a combination of factors, including reduced stress hormones, sensory engagement, and exposure to naturally occurring compounds released by trees.
Cardiovascular and metabolic health
Forest therapy has been associated with markers linked to reduced risk of chronic disease.
Studies have observed:
• Lowered blood pressure and heart rate
• Improved blood sugar regulation
• Reduced physiological stress load
Together, these effects suggest that regular time in nature may help support cardiovascular and metabolic health, particularly when combined with other healthy lifestyle practices.
Mental health, mood, and cognitive well-being
A substantial body of research explores the psychological and emotional benefits of forest therapy and nature exposure. Reported benefits include:
• Improved mood and emotional stability
• Reduced anxiety, anger, depression, and rumination
• Increased feelings of vitality and mental clarity
• Improved sleep quality
• Enhanced cognitive function and attention
Systematic reviews and controlled studies suggest forest therapy may be especially helpful as a supportive practice for individuals experiencing chronic stress, depression, or emotional fatigue.
Quality of life for people living with and beyond cancer
Emerging research indicates that nature-based interventions may help improve quality of life for cancer survivors. Findings suggest potential benefits such as:
• Reduced stress and emotional burden
• Improved mood and overall well-being
• Support for coping during and after treatment
These interventions are increasingly explored as complementary approaches within integrative and survivorship care.
Pain management and physical comfort
Forest therapy has also been studied in relation to chronic pain conditions. Research suggests it may help:
• Reduce perceived pain intensity
• Improve coping with chronic widespread pain
• Support both physiological relaxation and psychological resilience
Burnout reduction and professional well-being
Preliminary studies suggest forest therapy may help reduce burnout and support resilience among healthcare professionals and other high-stress occupations by fostering rest, reflection, and social connection in restorative environments.
Selected studies
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Chen H, Meng Z, Luo J. Is forest bathing a panacea for mental health problems? A narrative review. Front Public Health. 2025 Feb 20;13:1454992. doi: 10.3389/fpubh.2025.1454992. PMID: 40051516; PMCID: PMC11882403.
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Li Q, Takayama N, Katsumata M, Takayama H, Kimura Y, Kumeda S, Miura T, Ichimiya T, Tan R, Shimomura H, Tateno A, Kitagawa T, Aoyagi Y, Imai M. Impacts of Forest Bathing (Shinrin-Yoku) in Female Participants with Depression/Depressive Tendencies. Diseases. 2025 Mar 28;13(4):100. doi: 10.3390/diseases13040100. PMID: 40277811; PMCID: PMC12026234.
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Queirolo L, Fazia T, Roccon A, Pistollato E, Gatti L, Bernardinelli L, Zanette G, Berrino F. Effects of forest bathing (Shinrin-yoku) in stressed people. Front Psychol. 2024 Nov 1;15:1458418. doi: 10.3389/fpsyg.2024.1458418. PMID: 39554703; PMCID: PMC11565252.
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Abookire SA, Ayala SG, Shadick NA. Supporting Wellness, Resilience, and Community With Forest Therapy. Glob Adv Integr Med Health. 2024 Apr 9;13:27536130241246503. doi: 10.1177/27536130241246503. PMID: 38601344; PMCID: PMC11005489.
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Sundermann M, Chielli D, Spell S. Nature As Medicine: The 7th (Unofficial) Pillar of Lifestyle Medicine. Am J Lifestyle Med. 2023 May 31;17(5):717-729. doi: 10.1177/15598276231174863. PMID: 37711353; PMCID: PMC10498981.
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Timko Olson ER, Olson AA, Driscoll M, Vermeesch AL. Nature-Based Interventions and Exposure among Cancer Survivors: A Scoping Review. Int J Environ Res Public Health. 2023 Jan 29;20(3):2376. doi: 10.3390/ijerph20032376. PMID: 36767741; PMCID: PMC9916332.
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Qiu Q, Yang L, He M, Gao W, Mar H, Li J, Wang G. The Effects of Forest Therapy on the Blood Pressure and Salivary Cortisol Levels of Urban Residents: A Meta-Analysis. Int J Environ Res Public Health. 2022 Dec 27;20(1):458. doi: 10.3390/ijerph20010458. PMID: 36612777; PMCID: PMC9819785.
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Yeon PS, Kim IO, Kang SN, Lee NE, Kim GY, Min GM, Chung CY, Lee JS, Kim JG, Shin WS. Effects of Urban Forest Therapy Program on Depression Patients. Int J Environ Res Public Health. 2022 Dec 28;20(1):507. doi: 10.3390/ijerph20010507. PMID: 36612825; PMCID: PMC9819035.
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Li Q, Ochiai H, Ochiai T, Takayama N, Kumeda S, Miura T, Aoyagi Y, Imai M. Effects of forest bathing (shinrin-yoku) on serotonin in serum, depressive symptoms and subjective sleep quality in middle-aged males. Environ Health Prev Med. 2022;27:44. doi: 10.1265/ehpm.22-00136. PMID: 36328588; PMCID: PMC9665960.
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Sudimac S, Sale V, Kühn S. How nature nurtures: Amygdala activity decreases as the result of a one-hour walk in nature. Mol Psychiatry. 2022 Nov;27(11):4446-4452. doi: 10.1038/s41380-022-01720-6. Epub 2022 Sep 5. PMID: 36059042; PMCID: PMC9734043.
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Yeon PS, Jeon JY, Jung MS, Min GM, Kim GY, Han KM, Shin MJ, Jo SH, Kim JG, Shin WS. Effect of Forest Therapy on Depression and Anxiety: A Systematic Review and Meta-Analysis. Int J Environ Res Public Health. 2021 Dec 1;18(23):12685. doi: 10.3390/ijerph182312685. PMID: 34886407; PMCID: PMC8657257.
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Chae Y, Lee S, Jo Y, Kang S, Park S, Kang H. The Effects of Forest Therapy on Immune Function. Int J Environ Res Public Health. 2021 Aug 10;18(16):8440. doi: 10.3390/ijerph18168440. PMID: 34444188; PMCID: PMC8394293.
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Kotera Y, Richardson M, Sheffield D. Effects of shinrin-yoku (forest bathing) and nature therapy on mental health: A systematic review and meta-analysis. Int J Ment Health Addiction. 2020; 20(1):337-361. doi:10.1007/s11469- 020-00363-4
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Antonelli M, Barbieri G, Donelli D. Effects of forest bathing (shinrin-yoku) on levels of cortisol as a stress biomarker: a systematic review and meta-analysis. Int J Biometeorol. 2019 Aug;63(8):1117-1134. doi: 10.1007/s00484-019-01717-x. Epub 2019 Apr 18. PMID: 31001682.
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Han JW, Choi H, Jeon YH, Yoon CH, Woo JM, Kim W. The Effects of Forest Therapy on Coping with Chronic Widespread Pain: Physiological and Psychological Differences between Participants in a Forest Therapy Program and a Control Group. Int J Environ Res Public Health. 2016 Feb 24;13(3):255. doi: 10.3390/ijerph13030255. PMID: 26927141; PMCID: PMC4808918.
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Bratman GN, Daily GC, Levy BJ, Gross JJ. The benefits of nature experience: Improved affect and cognition. Landsc Urban Plann. 2015;138:41-50. doi:10.1016/j.landurbplan.2015.02.005
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Lee J, Park BJ, Tsunetsugu Y, Ohira T, Kagawa T, Miyazaki Y. Effect of forest bathing on physiological and psychological responses in young Japanese male subjects. Public Health. 2011 Feb;125(2):93-100. doi: 10.1016/j.puhe.2010.09.005. Epub 2011 Feb 1. Erratum in: Public Health. 2019 Apr;169:201. doi: 10.1016/j.puhe.2019.03.002. PMID: 21288543.
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Park BJ, Tsunetsugu Y, Kasetani T, Kagawa T, Miyazaki Y. The physiological effects of Shinrin-yoku (taking in the forest atmosphere or forest bathing): evidence from field experiments in 24 forests across Japan. Environ Health Prev Med. 2010 Jan;15(1):18-26. doi: 10.1007/s12199-009-0086-9. PMID: 19568835; PMCID: PMC2793346.
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Li Q. Effect of forest bathing trips on human immune function. Environ Health Prev Med. 2010 Jan;15(1):9-17. doi: 10.1007/s12199-008-0068-3. PMID: 19568839; PMCID: PMC2793341.
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Li Q, Morimoto K, Nakadai A, Inagaki H, Katsumata M, Shimizu T, Hirata Y, Hirata K, Suzuki H, Miyazaki Y, Kagawa T, Koyama Y, Ohira T, Takayama N, Krensky AM, Kawada T. Forest bathing enhances human natural killer activity and expression of anti-cancer proteins. Int J Immunopathol Pharmacol. 2007 Apr-Jun;20(2 Suppl 2):3-8. doi: 10.1177/03946320070200S202. PMID: 17903349.
